Abstracts / Extended Abstracts/Journal Articleshttp://repository.rjt.ac.lk/handle/123456789/14042026-04-05T20:35:14Z2026-04-05T20:35:14ZAn in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venomKakumanu, RahiniHarper, Barbara K.Kemp.Silva, AnjanaKuruppu, SanjayaIsbister, Geofferey K.Hodgson, Wayne C.http://repository.rjt.ac.lk/handle/123456789/55252025-10-10T04:39:42Z2019-01-01T00:00:00ZAn in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom
Kakumanu, Rahini; Harper, Barbara K.Kemp.; Silva, Anjana; Kuruppu, Sanjaya; Isbister, Geofferey K.; Hodgson, Wayne C.
2019-01-01T00:00:00ZSub-clinical neuromuscular dysfunction after envenoming by Merrem’s hump-nosed pit viper (Hypnale hypnaleSilva, AnjanaSegwick, E.MichaelWeerawansa, PrasannaPilapitiya, SenakaWeerasinghe, VajiraSiribaddana, SisiraIsbister, Geoffrey K.http://repository.rjt.ac.lk/handle/123456789/54722025-10-10T03:57:39Z2019-01-01T00:00:00ZSub-clinical neuromuscular dysfunction after envenoming by Merrem’s hump-nosed pit viper (Hypnale hypnale
Silva, Anjana; Segwick, E.Michael; Weerawansa, Prasanna; Pilapitiya, Senaka; Weerasinghe, Vajira; Siribaddana, Sisira; Isbister, Geoffrey K.
2019-01-01T00:00:00ZComparison of Kato Katz, antibody-based ELISA and droplet digital PCR diagnosis of schistosomiasis japonica: Lessons learnt from a setting of low infection intensityCaiI, PengfeiWeerakoon, Kosala G.Mu, YiOlveda, Remigio M.Ross, Allen G.Olveda, David U.McManus, Donald P.http://repository.rjt.ac.lk/handle/123456789/54672025-10-10T03:07:25Z2019-03-04T00:00:00ZComparison of Kato Katz, antibody-based ELISA and droplet digital PCR diagnosis of schistosomiasis japonica: Lessons learnt from a setting of low infection intensity
CaiI, Pengfei; Weerakoon, Kosala G.; Mu, Yi; Olveda, Remigio M.; Ross, Allen G.; Olveda, David U.; McManus, Donald P.
2019-03-04T00:00:00ZMelioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case reportPathirage, Manoji.M.KKularatne, Senanayake.A.MWeerakoon, Kosala.Ghttp://repository.rjt.ac.lk/handle/123456789/54142025-10-10T03:31:01Z2019-04-30T00:00:00ZMelioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case report
Pathirage, Manoji.M.K; Kularatne, Senanayake.A.M; Weerakoon, Kosala.G
Background: Melioidosis is a potentially fatal bacterial infection caused by Burkholderia pseudomallei. The existence
of melioidosis in Sri Lanka was once unheard of, and entertaining it as a diagnosis in clinical practice was extremely
rare.
Case presentation: In this case report, we describe the clinical, epidemiological, and longitudinal follow-up data of
a 58-year-old previously healthy Sinhalese woman who presented to our hospital with protracted febrile illness of 5
weeks’ duration, later developing multiple abscesses at different sites of the body. There was a significant delay in
confirming the diagnosis of melioidosis by isolating B. pseudomallei from blood and pus cultures. The patient
recovered fully with a prolonged course of antibiotics and has remained in good health over the last 13 years
without recurrence. Despite being immunocompetent, she had contracted the infection by a brief contact with
mud soil in a footpath.
Conclusions: A high index of clinical suspicion along with laboratory support is needed to confirm the diagnosis of
melioidosis. Treatment with sensitive antibiotics over a long duration is needed, and longitudinal follow-up is
essential to detect recurrences. This case raised awareness and created renewed interest in studies of melioidosis in
Sri Lanka.
Keywords: Burkholderia pseudomallei, Melioidosis, Sri Lanka
2019-04-30T00:00:00Z