http://repository.rjt.ac.lk/handle/123456789/1404 2026-04-05T20:34:48Z http://repository.rjt.ac.lk/handle/123456789/5525 An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom Kakumanu, Rahini; Harper, Barbara K.Kemp.; Silva, Anjana; Kuruppu, Sanjaya; Isbister, Geofferey K.; Hodgson, Wayne C. 2019-01-01T00:00:00Z http://repository.rjt.ac.lk/handle/123456789/5472 Sub-clinical neuromuscular dysfunction after envenoming by Merrem’s hump-nosed pit viper (Hypnale hypnale Silva, Anjana; Segwick, E.Michael; Weerawansa, Prasanna; Pilapitiya, Senaka; Weerasinghe, Vajira; Siribaddana, Sisira; Isbister, Geoffrey K. 2019-01-01T00:00:00Z http://repository.rjt.ac.lk/handle/123456789/5467 Comparison of Kato Katz, antibody-based ELISA and droplet digital PCR diagnosis of schistosomiasis japonica: Lessons learnt from a setting of low infection intensity CaiI, Pengfei; Weerakoon, Kosala G.; Mu, Yi; Olveda, Remigio M.; Ross, Allen G.; Olveda, David U.; McManus, Donald P. 2019-03-04T00:00:00Z http://repository.rjt.ac.lk/handle/123456789/5414 Melioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case report Pathirage, Manoji.M.K; Kularatne, Senanayake.A.M; Weerakoon, Kosala.G Background: Melioidosis is a potentially fatal bacterial infection caused by Burkholderia pseudomallei. The existence of melioidosis in Sri Lanka was once unheard of, and entertaining it as a diagnosis in clinical practice was extremely rare. Case presentation: In this case report, we describe the clinical, epidemiological, and longitudinal follow-up data of a 58-year-old previously healthy Sinhalese woman who presented to our hospital with protracted febrile illness of 5 weeks’ duration, later developing multiple abscesses at different sites of the body. There was a significant delay in confirming the diagnosis of melioidosis by isolating B. pseudomallei from blood and pus cultures. The patient recovered fully with a prolonged course of antibiotics and has remained in good health over the last 13 years without recurrence. Despite being immunocompetent, she had contracted the infection by a brief contact with mud soil in a footpath. Conclusions: A high index of clinical suspicion along with laboratory support is needed to confirm the diagnosis of melioidosis. Treatment with sensitive antibiotics over a long duration is needed, and longitudinal follow-up is essential to detect recurrences. This case raised awareness and created renewed interest in studies of melioidosis in Sri Lanka. Keywords: Burkholderia pseudomallei, Melioidosis, Sri Lanka 2019-04-30T00:00:00Z