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Department of Medicine: Recent submissions

  • Understanding of research: a Sri Lankan perspective 
    Sumathipala, A.; Siribaddana, Sisira; Hewage, S.N.; Lekmawattege, M.; Athukorala; Siriwardane, C.; Munasingha, K.; Murray, J.; Prince, M. (Springer Nature, 4/27/2010)
    Lack of proper understanding on the part of researchers about public understanding of research and informed consent will increase the potential for malpractice. As a part of a larger study on ethics and informed consent ...
  • Environmental exposures and their genetic or environmental contribution to depression and fatigue: A twin study in Sri Lanka 
    Ball, H.; Siribaddana, Sisira; Sumathipala, A.; Kovas, Y.; Glozier, N.; Guffin P, M.C.; Hotopf, M. (Springer Nature, 2/2/2010)
    Background There is very little genetically informative research identifying true environmental risks for psychiatric conditions. These may be best explored in regions with diverse environmental exposures. The current study ...
  • Epidemiology and symptomatology of depression in Sri Lanka: A cross-sectional population-based survey in Colombo District 
    Ball, H.; Siribaddana, Sisira; Kovas, Y.; Glozier, N.; Guffin P, M.C.; Sumathipala, A.; Hotopf, M. (Elsevier, 2010-06)
    Background It is important to understand the nature of depression in non-Western and lower-income countries, but little such research exists. This study aimed to examine the characteristic features of depression in Sri ...
  • Genetic and environmental contributions to depression in Sri Lanka 
    Ball, H.; Sumathipala, A.; Siribaddana, Sisira; Kovas, Y.; Glozier, N.; Guffin P, M.C.; Hotopf, M. (Cambridge University Press, 2009-12)
    Background Susceptibility to depression results from genetic and non-familially shared environmental influences in high-income, Western countries. Environments may play a different role for populations in different ...
  • Colombo Twin and Singleton Study (CoTASS): A description of a population based twin study of mental disorders in Sri Lanka 
    Siribaddana, Sisira; Ball, H.A.; Hewage, S.N.; Glozier, N.; Kovas, Y.; Dayaratne, D.A.R.K.; Sumathipala, A.; Guffin P, M.C.; Hotopf, M. (Springer Nature, 2008-02)
    Background The Sri Lankan twin registry is one of the first to be established in a developing country, and its design has ensured sampling from a wide range of environmental conditions. It thus has great potential to ...
  • Quantitative Ultrasound of Bone and Calcium Intake in Sub-Urban Males in Sri Lanka 
    Siribaddana, Sisira; Kovas, Y.; Fernando, D.J.S. (John Wiley & Sons, 2008-11)
    Background: While only 30% of all hip fractures occurred in Asia in 1990, more than 50% will occur by the year 2050. We investigated the relationship between the Stiffness Index (SI), assessed with quantitative ultrasound, ...
  • Update From Sri Lankan Twin Registry: Establishment of a Population-Based Twin Register and Ongoing Project on Common Mental Disorders, Alcohol Abuse and Suicidal Ideations 
    Siribaddana, Sisira; Siriwardane, W.D.; Hewage, S.N.; Athukorale, A.D.M.D.; Sumathipala, A.; Hotopf, M. (Cambridge University Press, 2006-12)
    The Sri Lankan Twin Registry began as a volunteer register in 1997. Previously, we have shown door-to-door surveys as the best option to build a population-based twin register of older, adult twins. Our aim was to build a ...
  • Management of dead bodies as a component of psychosocial interventions after the tsunami: A view from Sri Lanka 
    Sumathipala, A.; Siribaddana, Sisira; Perera, Clifford (Taylor and Francis, 2006-07)
    Even if predicted, disasters may not be completely averted due to reasons beyond human control. There is always likely to be a degree of loss, human as well as material. Therefore, the correct strategy is to limit the ...
  • Research and clinical ethics after the tsunami: Sri Lanka 
    Sumathipala, A.; Siribaddana, Sisira (Science Direct, 2005-10)
    In late 2004, the Journal of Traumatic Stress published a special section about the ethics of disaster research, addressing ethical issues related to conducting research after disasters and terrorist attacks, and based on ...
  • Osteoporosis in Sri Lanka 
    Siribaddana, Sisira; Lekamwasam, S. (Research Gate, 2004-10)
    In Sri Lanka the median age, which was 25 in year 1991, is expected to rise to 45 by the year 2041 and half of the population will be over 45 years and vulnerable to osteoporosis. We describe 2 large epidemiological studies ...
  • Hope of prevention training in South Asia 
    Dodani, Sunita; Pandav, Chandrakant S.; Siribaddana, Sisira; Laporte, Ronald; Pokharel, Paras (Research Gate, 7/29/2004)
    EDITOR—The theme issue on Health in South Asia in April addressed problems and hopes for health but neglected prevention. South Asia has a quarter of the world's population. The optimal means to improve health is public ...
  • Culture-bound syndromes: the story of dhat syndrome 
    Sumathipala, A.; Siribaddana, Sisira; Bhugra, D. (Cambridge University Press, 2004-03)
    Background Culture-bound syndrome is a term used to describe the uniqueness of some syndromes in specific cultures. Dhat (semen-loss anxiety) has been considered to be an exotic ‘neurosis of the Orient’. Aims To ...
  • Capacity building through multi-disciplinary research: a report from Sri Lanka 
    Sumathipala, A.; Siribaddana, Sisira; Samaraweera, S.; Dayaratne, D.A.R.K. (Cambridge University Press, 2003-11)
    Sri Lanka is an island situated close to the southern tip of the Indian subcontinent with a land area of about 65 000 km2. The population in 2001 was 18.5 million. It has an interesting genetic diversity, its five main ...
  • Challenges in Recruiting Older Twins for the Sri Lankan Twin Registry 
    Sumathipala, A.; Siribaddana, Sisira; Fernando, D.S.J.; Abeysinghe, M.R.N.; De Silva, N.; Hotopf, M. (Cambridge university, 2003-02)
    The National Twin Registry of Sri Lanka was established in 1997 as a volunteer register. To extend it to a population-based register, we examined the effectiveness of tracing older twins by inspecting birth records and ...
  • Qualitative Research 
    Sumathipala, A.; Siribaddana, Sisira; De Silva, N. (Research Gate, 2004-01)
  • Increasing diabetes and vascular risk factors in a sub-urban Sri Lankan population 
    Malavige, G.N.; De Alwis, N.M.; Weerasuriya, N.; Fernando, D.J.S.; Siribaddana, Sisira (Research Gate, 2002-09)
    Increasing numbers of developing nations experience a rising incidence of non-communicable diseases in parallel with economic development. Thus, developing countries such as Sri Lanka face the double burden of both ...
  • Sri Lankan Twin Registry 
    Sumathipala, A.; Siribaddana, Sisira; De Silva, N.; Fernando, D.S.J.; Abeysinghe, M.R.N.; Dayaratne, R.; De Silva, D.; Warnasuriya, N.; Hotopf, M. (Research Gate, 2002-11)
    Sri Lanka is an island with genetic diversity between the five main population groups. Our twin registry is the first in the developing world. Initially, we established a volunteer cohort of 4600 twin pairs through a ...
  • Feasibility of Using Different Approaches for Recruiting Younger Twins to Establish A Population Based Twin Register in Sri Lanka 
    Sumathipala, A.; Siribaddana, Sisira; Fernando, D.S.J.; Abeysinghe, M.R.N.; De Silva, N.; Sivayogam, S. (Research Gate, 2001-01)
    I dentifying twins for a population-based register can be achieved through birth records or community surveys. We studied the feasibility and effectiveness of different methods of identifying and recruiting twins to establish ...
  • Cross-cultural adaptation and preliminary validation of a zygosity determination questionnaire for twins in Sri Lanka 
    Sumathipala, A.; De Silva, N.; Siribaddana, Sisira; Fernando, D.S.J.; Abeysinghe, M.R.N. (Research Gate, 2001-01)
    We report the process of adaptation into Sinhala of a questionnaire given to mothers of twins to determine zygosity. Adaptation and validation was carried out in three stages. Firstly, we used a nominal group to translate ...
  • Establishing a twin register in Sri Lanka 
    Sumathipala, A.; Fernando, D.S.J.; Siribaddana, Sisira; Abeysinghe, M.R.N.; De Silva, N.; Dissanayake, V.; Jayasekare, R.W. (Research Gate, 2000-12)
    Nearly all twin registers are based in developed countries and there is no twin register in the developing world. Our objectives were to initiate the process of establishing a nationwide twin register in Sri Lanka by ...

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