Abstract:
Introduction. Biobanks are a valuable resource for creating advancements in science through
cutting-edge omics research. Twin research methods allow us to understand the degree to
which genetics and environmental factors contribute to health outcomes.
Methods. The Sri Lankan Twin Registry biobank (SLTR-b) was established in 2015 as part of
Colombo Twin and Singleton Follow-up Study. Venous blood and urine were collected from
twins and comparative sample of singletons for clinical investigations and biobanking.
Results. The SLTR-b currently houses 3369 DNA and serum samples. Biobank specimens are
linked to longitudinal questionnaire data, clinical investigations, anthropometric measure ments, and other data.
Discussion. The SLTR-b aims to address gaps in health and genetics research. It will provide
opportunities for academic collaborations, local and international, and capacity building of
future research leaders in twin and omics research. This paper provides a cohort profile of
the SLTR-b and its linked data, and an overview of the strategies used for biobanking.
